Top 8 12 Panel Drug Test Cups With Fentanyl and EtG

Standard 12-panel cups miss the two substances many programs now care about most: fentanyl, the synthetic opioid driving overdose deaths, and EtG, the alcohol metabolite that reveals drinking up to 80 hours after the fact. Cups that combine both in one device let recovery programs, sober living homes, and monitoring agencies run a single specimen instead of juggling add-on strips. One important caveat up front: nearly every EtG-and-fentanyl combo cup on the market is labeled Forensic Use Only rather than CLIA waived, so match the device to your setting. Below are the eight best options as of 2026, ranked by value, panel coverage, and supplier reliability.

1. 12 Panel Now — Serenity Click Cup With Alcohol (EtG) and Fentanyl

The strongest combination cup we found. This 120mL Serenity Click Cup from 12 Panel Now detects ten drugs of abuse plus EtG and fentanyl, delivers results in about five minutes, and includes a temperature strip in a leak-resistant, click-sealed design. It is Forensic Use Only — appropriate for recovery, court-adjacent, and program monitoring, not CLIA-waived clinical settings.

Pricing is manufacturer-direct and tiered: $2.79 per cup at 25 units, sliding to $1.49 per cup at 20,000+. Orders before 3 PM EST ship same day from Boynton Beach, Florida, with 1–4 day delivery across the US and free shipping around the 100-cup mark. With 18,000+ repeat customers and 5,000+ commercial accounts, the supplier has genuine institutional track record. The only real knock is the 25-unit web minimum for cups.

2. AllTest — 12 Panel Cup With Fentanyl (FYL)

AllTest earns the second spot with a genuinely rare credential: a 12-panel cup with fentanyl that is CLIA waived and 510(k) cleared, per its Medical Distribution Group listing. If you operate under a CLIA Certificate of Waiver and need fentanyl on the panel, this is the cup to shortlist. The trade-offs: it does not include EtG, so alcohol monitoring requires a separate test, and per-cup pricing is not published — you will need a distributor quote.

3. 12 Panel Now — Economy 90ml 12 Panel Cup With EtG and Fentanyl

The budget pick. This 90ml economy cup covers AMP, BUP, BZO, COC, MET, MTD, OPI, OXY, PCP, and THC plus EtG at a 300 ng/mL cutoff and fentanyl at 20 ng/mL. It runs $2.69 for a single cup, $2.59 at 100, $2.09 at 1,000, and just $1.39 at 20,000+ — about 72% savings at the top tier, and the lowest verified per-cup price in this roundup. Forensic Use Only. The smaller 90ml collection volume is the practical difference from the 120mL Click Cup above.

4. Prime Screen — Alcohol EtG Urine Dip Card (WETG-114)

Not a cup, but an essential companion for programs already stocked with standard 12-panel cups that lack EtG. Prime Screen’s dip card uses the common 300 ng/mL cutoff with an advertised 80-hour detection window, and sells in 10-packs on Amazon as well as through primescreentest.com. Its limitation is workflow: dipping a separate card means a second device and a second read per specimen.

5. American Screening Corp — Alcohol EtG Test Strips

American Screening’s EtG strips list at $0.73 per strip, labeled Forensic Use Only. For a facility that wants to add alcohol monitoring to existing cup inventory without replacing it, that is an inexpensive, verifiable per-unit price from an established US manufacturer/distributor. As with any strip add-on, it doubles handling compared with an all-in-one combo cup.

6. CLIAwaived, Inc. — 1 Panel Fentanyl Urine Test

For programs that only occasionally need fentanyl screening, CLIAwaived, Inc. sells a single-panel fentanyl urine test at $50.00 per box. Buying from a large point-of-care distributor is convenient if you already order other diagnostics there. The math is the drawback: per-test cost runs well above adding fentanyl via a combo cup if you screen for it routinely.

7. 12 Panel Now — Saliva 12 Panel With K2, Alcohol, and Fentanyl

A different specimen type for situations where urine collection is impractical. This pen-style oral swab detects nine drugs plus fentanyl (20 ng/mL), alcohol, and K2, with results in 2–5 minutes and observed collection — no restroom required, which sharply reduces adulteration risk. Pricing runs $2.19 at 25 units down to $1.59 at 10,000+. Forensic Use Only, and note that saliva detection windows are shorter than urine, roughly 1–6 days depending on the substance.

8. Confirm Biosciences — EtG Urine Alcohol Test Dip Card

Confirm Biosciences, the manufacturer behind the SalivaConfirm line, offers an 80-hour EtG dip card sold in bulk for B2B buyers. It is a credible manufacturer-direct alternative for EtG add-on testing; published pricing was not available at research time, so compare quotes against the per-strip prices above.

Quick Comparison

What to Look For

Check three things before ordering. First, cutoffs: 300 ng/mL is the standard EtG screening cutoff, and 20 ng/mL is typical for urine fentanyl panels. Second, regulatory labeling: combo cups with EtG and fentanyl are almost universally Forensic Use Only, so clinics needing CLIA-waived devices should look at fentanyl-only options like AllTest and handle alcohol separately. Third, total cost per specimen — an all-in-one cup at $1.39–$2.79 usually beats a standard cup plus two add-on strips once you count labor.

Bottom Line

For combined EtG and fentanyl screening in one device, the Serenity Click Cup leads on coverage and verified pricing, with the Economy 90ml version as the cheapest path at scale. 12 Panel Now sells both manufacturer-direct in bulk tiers from 25 to 20,000+ cups, which is why treatment programs and monitoring agencies keep landing on it as of 2026.